Discrete Global Grid Systems (DGGS) have many advantages over traditional coordinate reference systems. A DGGS is a spatial reference system consisting of multiple layers of grids with increasing resolution which partition the globe into polygon shaped cells of equal area. Individual cells can be easily identified and basic Geographic Information System (GIS) operations can be performed on data stored within the cells. Advantages of using DGGS for spatial data include the ability to integrate data layers of different data types in a statistically uniform way, the possibility to avoid distortions caused from projection, and the capability to scale analysis across multiple resolution levels. The benefits of using DGGS for hydrographic data, specifically Electronic Navigational Charts (ENC) are examined. The addition of DGGS to S-100 would provide a uniform gridding system for ENC cells, and would eliminate distortions in the Polar Regions caused when projecting rectangular cells based on latitude and longitude. The Open Geospatial Consortium (OGC) led a pilot project for which one of the participants developed a server that offers S-100 marine protected area data organized according to DGGS. Because of this success and the availability of open-source software for the implementation of DGGS, the BSH (German Federal Maritime and Hydrographic Agency) investigated the feasibility and possible benefits of using Discrete Global Grid Systems for S-100 data. The outcome was successful. However, it is recognized that DGGS as a standard is not yet advanced enough and the available software tools are inadequate for wide implementation. More investigation needs to be done, and additionally the best grid shape, orientation and aperture for a uniform grid for hydrographic data need to be determined. Overall, DGGS should be considered for future versions of S-100, the new universal hydrographic data model, because the benefits for ENCs and hydrographic data are clear and in the future, it is expected that DGGS will revolutionize GIS.